ABSTRACT
INTRODUCCIÓN: El Carcinoma basocelular (CBC) es la neoplasia más frecuente en la población humana. Se ha observado un aumento de su incidencia en todos los países, incluyendo a Chile. CBC es un tumor heterogéneo clínica e histológicamente. Entre sus factores de riesgo, destaca la exposición a la radiación ultravioleta. En Chile, en la última década se han realizado numerosas campañas de prevención del cáncer cutáneo y de detección precoz de esta neoplasia. El propósito de este trabajo es comparar el comportamiento del CBC en relación a parámetros demográficos, clínicos e histológicos en dos periodos de tiempo, 1995-1999 y 2005-2009 en la población de cuatro hospitales públicos de Santiago de Chile...
INTRODUCTION: Basal cell carcinoma (BCC) is the most common malignancy in the human population. There has been an increased incidence in all countries, including Chile. BCC is a clinically and histologically heterogeneous tumor. The main risk factor of BCC is the ultraviolet radiation exposure. In Chile, in the last decade, there have been numerous campaigns of skin cancer prevention and early detection of this neoplasm. The purpose of this paper is to compare the behavior of BCC in relation to demographic, clinical and histological parameters in two periods, 1995-1999 and 2005-2009 in the population of four hospitals in Santiago de Chile
Subject(s)
Humans , Male , Adolescent , Psoriasis/epidemiology , Chile , Sex Factors , Epidemiology, Descriptive , Prevalence , Prospective Studies , Age of Onset , Age and Sex DistributionSubject(s)
Humans , Adult , Female , Skin Neoplasms/diagnosis , Skin Neoplasms/pathology , Nevus/diagnosis , Nevus/pathology , InflammationSubject(s)
Humans , Adult , Female , Ichthyosis/pathology , Ichthyosis/therapy , Face , Neck , Radio Waves/therapeutic useABSTRACT
Introducción: La micosis fungoides (MF) es el linfoma cutáneo de células T más frecuente. Se presenta de diversas formas clínicas, siendo la micosis fungoides hipopigmentada una variante clínica poco común, sobre todo en población caucásica. Objetivo general: Describir los hallazgos clínicos y anatomopatológicos de la serie de pacientes con diagnóstico de MF hipopigmentada. Material y método: Estudio descriptivo, retrospectivo. Se analizaron todos los casos de MF hipopigmentada diagnosticados en el período 2004-2009 en tres centros de atención dermatológica. Resultados: Se describen siete pacientes con diagnóstico de MF hipopigmentada; el estudio histológico confirmó el diagnóstico en todos los casos, con un período de seguimiento de seis a 66 meses. El promedio de edad al momento del diagnóstico fue de 20,5 años. La inmunohistoquímica en todos los pacientes fue CD8 +, y seis de los siete pacientes evaluados fueron CD4 +. Cinco de los pacientes fueron manejados con PUVA, y de ellos todos lograron la remisión completa.
Introduction:: Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma. It manifests in diverse clinical forms, and a rare variant of MF is hypopigmented mycosis fungoides. Objective: To describe clinical, pathological and immunohistochemicol findings in a group of 7 hypopigmented MF patients. Material and methods: This is a descriptive and retrospective study. We analyzed all patients with diagnosis of hypopigmented MF during the 2004-2009 period in three dermatological centers. Results: We describe 7 patients diagnosed with hypopigmented MF Histological biopsies confirmed the diagnosis in all cases. The follow-up period was 6 to 66 months. The mean age at diagnosis was 20.5 years. Immunohistochemically, all patients were CD8 + and six were CD4 +. Treatment in five cases was with PUVA, which led to complete clinical remission.
Subject(s)
Humans , Male , Adolescent , Adult , Female , Hypopigmentation/pathology , Mycosis Fungoides/pathology , Skin Neoplasms/pathology , Biopsy , Hypopigmentation/drug therapy , Immunohistochemistry , Mycosis Fungoides/drug therapy , Skin Neoplasms/drug therapy , PUVA Therapy , Retrospective StudiesABSTRACT
Background: The Female Sexual Function index (FSFI), is a scale designed to evaluate sexuality and diagnose the presence of sexual dysfunction in women. Aim: To apply the FSFI to climacteric women. Patients and methods: The FSFI was applied to 370 healthy women aged between 40 and 59years old (49 ± 6years) that accompanied patients to public health services in Santiago. Results: Fifty six percent of women were married, 44 percent were postmenopausal, 6 percent used hormone replacement therapy, 67 percent were sexually active, and sexual dysfunction was present in 57 percent of them. Thirty two percent of women aged between 40 and 44 years and 65 percent of women aged between 55 and 59 years, had sexual dysfunction (p <0.01). In a logistic regression model, the risk of sexual dysfunction increased among women that perceive having health problems (Odds ratio (OR) 3-9; 95 percento confidence intervals (95 percent CI): 1.1-13-8), women older than 48 years (OR 1.9; 95 percent CI: 1.1-3-4) and women that gave birth to two or more children (OR 1.8; 95 percent CI: 1.0-3-1). Conclusions: Climateric women have high prevalence of sexual dysfunction. Age is its main risk factor.